RECOVERY® Ingredients

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When a cell is irritated or damaged, or when it begins to age, its membranes break down. As a result, compounds contained within the cell walls are released into the cellular matrix. Some of these substances, such as histamine, give rise to inflammation and associated pain.

The ingredients in RECOVERY® are skillfully and carefully combined to help stabilize cell membranes, ensuring that you  derive maximum benefit. RECOVERY® ingredients work synergistically within the body to maximize health and wellbeing…

Nutricol®:

First and foremost in the quest to quell the processes that result in pain is our proprietary ingredient, Nutricol®. Consisting  of the polyphenols, epigallocatechin gallate (EGCg) from green tea,  and grapeseed extract, as well as the proanthocyanidins, theaflavin and resveratrol, Nutricol®’s  ingredients empower each other to increase cell membrane receptivity to hormones such as insulin, IGF, and thyroxin. These hormones are an important requirement for the processes involved in building/healing to take place.  Improved cell membranes also allow the cells to better absorb and benefit from nutrients such as glucosamine in foods and supplements, increasing tissue health and overall quality of life.

Let’s take a closer look at how the ingredients in Nutricol® facilitate the healing process.

EGCg and Grapeseed extract

Both important polyphenols, EGCg and grapeseed extract have been shown to inhibit the processes that lead to inflammation. This is largely attributable to their high antioxidant activity along with their ability to increase activity of the body’s own antioxidant and detoxification systems. In a 1999 University of Kansas study,  researchers found that green tea is at least 100 times more effective than vitamin C and 25 times better than vitamin E at protecting cells and their genetic material, DNA, from damage1.  Green tea polyphenols have also been shown to suppress inflammatory prostaglandin-E2 —a hormone-like substance that contributes towards arthritis and other inflammatory conditions. A 2004 laboratory study at the University of Sheffield in England found that EGCg may help prevent osteoarthritis by blocking the enzyme that destroys cartilage2.

NF-κB is a protein complex that, among other important functions, regulates the immune response within our bodies.  The inappropriate or overactivity of NF-κB  has been linked to the development of inflammation and autoimmune diseases. Both green tea and grapeseed extract block the NF-kB pathway that leads to cellular inflammation3,4.

Theaflavin and Resveratrol

Theaflavins from black tea (green tea that has been oxidized) have been shown to regulate the genes that produce inflammatory cytokines and other damaging factors associated with degenerative disease and aging. By suppressing inflammation at its earliest stages, theaflavins help prevent and control the advancement of inflammation-related diseases5.  Theaflavin also helps block the long-term effects of inflammation by blocking the action of inflammatory cytokines already present in the body. This prevents increased oxidation, further inflammation of the tissues, and the risk for chronic disease.

Resveratrol

Produced from grape skins, resveratrol has been shown to inhibit the enzymes primarily responsible for inflammation6,7. This reduces the production of inflammatory molecules, further suppressing pain.

Resveratrol is also a powerful antioxidant, helping protect tissues from free radical damage resulting from injury and/or inflammation.

Together, the ingredients of Nutricol provide the synergistic mechanisms required to halt inflammation in its earliest stages, strengthen cell walls to further quell damage resulting from ongoing inflammation, and restrict the processes that lead to tissue breakdown. The result is healthier tissues and associated reduction of pain.

Hyaluronic acid

Hyaluronic acid (HA) is a fluid carbohydrate, naturally present in various body tissues. When we are young, our bodies produce a lot of it but, as we age, its production lessens significantly. (It has been estimated that by the time we reach our mid-40s, the synthesis of HA is close to half that required by the body to function optimally.)  As well as having anti-inflammatory and antioxidant activity, HA cushions the joint and nerve tissues, acting as a shock absorber and increasing comfort during movement. It also stabilizes the breakdown of fluids within the joint tissues.

In 2005, researchers at the University of California, Irvine, established that HA levels in osteoarthritic joints are below normal8, suggesting that HA supplementation can, to a degree, prevent the pain caused by wear and tear of the joints.  This was confirmed in a 2008 double-blind clinical trial involving 20 patients with osteoarthritis of the knee.

Ten of the study participants received 80 mg. of hyaluronic acid daily while 10 were given a placebo. After eight weeks, those taking the hyaluronic acid supplements reported experiencing less joint pain and enjoying a better quality of life when compared with those in the placebo group9.

Methylsulfonylmethane (MSM)

MSM is a naturally occurring sulfur compound found inside our bodies as well as in many of the foods we consume. It serves as an important source of dietary sulfur—a mineral that is critical to the maintenance of healthy joints and connective tissues.

In addition to quelling inflammation, MSM also helps the body to produce the important antioxidant, glutathione.

In one double-blind clinical trial, randomized, 50 men and women, 40-76 years of age with knee osteoarthritis  pain were given either MSM or a placebo. After 12 weeks, those who had taken MSM reported significant pain reduction compared with their counterparts who had been given a placebo10.

Glucosamine HCL

Glucosamine is a naturally occurring substance found in the fluid around our joints. It works to support the structural framework of healthy joints, promoting their mobility, range of motion and flexibility.

Glucosamine Hydrochloride contains more elemental glucosamine per mg than glucosamine sulfate and is more readily absorbed. Since most clinical trials have utilized glucosamine sulfate, the health supplement community relies on anecdotal evidence regarding the positive effects of glucosamine HCL on joint pain.

Betaine HCL

Betaine Hydrochloride is a crystalline alcohol derived from beets. It helps improve the process of digestion by increasing stomach acid levels. The poor digestion of foods, particularly proteins, can lead to digestive problems and poor absorption of nutrients. In turn, this can lead to vitamin deficiencies and food allergies when inadequately digested proteins are absorbed through the gut wall.  Many people who suffer from rheumatoid arthritis (RA) have increased intestinal permeability, especially when experiencing symptoms11.

Betaine also helps decrease lactic acid production and discomfort following exercise. Many athletes say it helps them work out longer and harder without the pain associated with the build-up of lactic acid.

As a methyl donor, betaine also participates in the methionine cycle within the liver and kidneys. (Reduced methylation can lead to a number of disease conditions including those of the heart and blood vessels, brain and liver.)

Magnesium

A vital mineral, magnesium is best recognized for the role it plays in bone strength and integrity, and for the proper functioning of the muscles. Magnesium and calcium work together to regulate electrical impulses within cells. Calcium enters the cell, triggers an electrical impulse, and is then escorted out of the cell by magnesium. Within the muscles, calcium contributes towards contraction, and magnesium to relaxation.  When magnesium levels are low, this process becomes less regulated, and may result in annoying twitches or painful spasms. People who take calcium supplements that do not include magnesium are particularly at risk for cramping and spasm.

Magnesium also helps to stabilize cell membranes and plays a role in over 300 enzyme processes within the body.

A lack of magnesium contributes towards the inflammatory process. As part of the inflammatory response, proteolytic (protein-dissolving) enzymes are produced and directed to the affected area to help counteract the inflammation. These enzymes are mediated by magnesium and have been shown to work less effectively when magnesium levels are low12.

Vitamin C

Vitamin C helps to produce collagen, the building block of our skin, cartilage, ligaments, and blood vessels.  A powerful antioxidant, vitamin C has also been shown to fight the inflammatory process. A 2008 study from the University of California, Berkeley, showed that vitamin C significantly lowered levels of C-reactive protein (CRP) a biomarker for inflammation13.

Vitamin E

Unlike water-soluble vitamin C, vitamin E is soluble in fats. Since the cell walls consist of lipids (fats), vitamin E’s antioxidant activity helps prevent damage to the cell walls caused by oxidation.  Vitamin C, however,  performs its antioxidant benefits in  the watery medium of the cellular interior. Thus vitamin C and E work together to protect and strengthen the cells and, ultimately, the tissues of the entire body.


1. Pillai SP, Mitscher LA, Menon SR, Pillai CA, Shankel DM. Antimutagenic/antioxidant activity of green tea components and related compounds. J Environ Pathol Toxicol Oncol. 1999;18(3):147-58.

2. Corps AN, Curry VA, Buttle DJ, Hazleman BL, Riley GP: Inhibition of interleukin-1beta-stimulated collagenase and stromelysin expression in human tendon fibroblasts by
epigallocatechin gallate ester.
Matrix Biol 2004 Jun;23(3):163-9.

3. Terra X, Valls J, Vitrac X, et al. Grape-seed procyanidins act as antiinflammatory agents in endotoxin-stimulated RAW 264.7 macrophages by inhibiting NFkB signaling pathway. J Agric Food Chem. 2007 May 30;55(11):4357-65.

4. Babu PV1, Si H, Liu D., Epigallocatechin gallate reduces vascular inflammation in db/db mice possibly through an NF-κB-mediated mechanism. Mol Nutr Food Res. 2012 Sep;56(9):1424-32.

5. Aneja R, Odoms K, Denenberg AG, Wong HR. Theaflavin, a black tea extract, is a novel anti-inflammatory compound. Crit Care Med. 2004 Oct;32(10):2097-103.

6. Subbaramaiah K, et al. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. Ann N Y Acad Sci. 1999;889:214-23.

7. Oi N, Jeong CH, Nadas J, et al. Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene ahydrolase. Cancer Res. 2010 Dec 1;70(23):9755-64.

8. Tehranzadeh J. Cartilage metabolism in osteoarthritis and the influence of viscosupplementation and steroid: a review. Acta Radiol. 2005;46:288-296.

9. Kalman DS. Effect of a natural extract of chicken combs with a high content of hyaluronic acid (Hyal-Joint) on pain relief and quality of life in subjects with knee osteoarthritis: a pilot randomized double-blind placebo-controlled trial. Nutrition Journal. 2008;7:3.

10. Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006 Mar;14(3):286-94. Epub 2005 Nov 23.

11. Cordain L, Toohey L, Smith MJ, Hickey MS. Modulation of immune function by dietary lectins in rheumatoid arthritis. Br J Nutr 2000;83(3):207–17.

12. Rayssiguier Y, Mazur A., Magnesium and inflammation: lessons from animal models. Clin Calcium. 2005 Feb;15(2):245-8

13. Block G, Jensen CD, Dalvi TB, Norkus EP, Hudes M, Crawford PB, Holland N, Fung EB, Schumacher L, Harmatz P., Vitamin C treatment reduces elevated C-reactive protein. Free Radic Biol Med. 2009 Jan 1;46(1):70-7. doi: 10.1016/j.freeradbiomed.2008.09.030.

 

63 Comments

  • Melissa says:

    Is this safe to take while breastfeeding?

    • Purica says:

      The NHPD says to take caution. The only thing we can say is that even one of the cofounders took Recovery throughout three pregnancies and breast feeding.
      Four teaspoons per day

  • Stephanie says:

    Can this be used to help with gout?

    • Purica says:

      Definitely! Add some black cherry juice in and you have a strong defence.

    • Purica says:

      Over the last fifteen plus years, many people have reported to us that Recovery has worked very well for their gout. Add some black cherry juice in and you have a strong defence.

  • Veronica says:

    What about the betaine HCL if you have digestive issues from too much acid such as GERD or a stomach ulcer?

    • Purica says:

      These levels would not affect ulcerations or GERD. Over many years of use, many people suffering from GERD who have used Recovery have noted positive benefits. Relief of heartburn is also a common side benefit with Recovery use.

  • norma says:

    Do you think Recovery is good for people that just were diagnosed with fibromyalgia? Thanks

    • Purica says:

      Over the years, there has been very positive feedback in regards to the benefits of RECOVERY from people stating they have Fibromyalgia.

  • Linda says:

    Does Recovery help provide relief from nerve pain caused by pinched nerves? Is it safe to take with prescription nerve pain medication (Lyrica)? Thank you

    • Purica says:

      Recovery is designed to help pain due to mechanical infringement and soft tissue damage, however, perhaps a chiropractor, physiotherapist, massage therapist, osteopath or acupuncturist would help to reboot the area, so to speak. The therapies work very well together, when there is mechanical impingement of nerves presenting.

  • dennis says:

    My elderly mother has bad arthritis and is on a drug called Hydroxchloroquine sulf ,200mg. Could your Recovery be taken along with this medication? Do you think Recovery would help regain some of her mobility? Thank you

    • Purica says:

      Recovery is designed to be safe to take with drugs. With over fifteen years of formal sales, we have had numerous reports of success with many people using it for different types of difficult to treat and late stage inflammatory conditions in both people and in animals, including joint inflammation and degeneration.

  • Manak says:

    Hi, I have a rotatory cuff problem on my left shoulder and a meniscus tear on my right knee. Would I be benefited by using Recovery? Thanks.

  • annette says:

    Hi there, I have a shellfish allergy and most Glucosamine supplements have shellfish extract in there. Does Recovery?

    Thanks.

    • Jason says:

      This is a frequently asked question, which we love to answer. Purica uses only glucosamine derived from plant source. There are no animal-derived substances.

  • Cheryl says:

    i have been takin purica recovery for almost 4’weeks(5 in the am and 5 at lunch. I find I feel worse with hip/knee joint pain. Is this normal

    • Purica says:

      Hello Cheryl,

      Thanks for your interest. With some people, when using Recovery it can result in the clearing of lodged immune complexes, and this may be accompanied by immune inflammatory bursts (a housekeeping type of response) until they are cleared.

      What seems to work best to accelerate the clearing is to increase the dose (perhaps adding another five caps per day) until the symptoms clear and then the dose can be adjusted to preference. Another option is to decrease the dose and gradually increase it over time to achieve the desired therapeutic serving size (this seems to take longer but typically avoids the experience of the clearing reaction).

      In short, this is typically part of the healing response for some users.

  • laura cerlon says:

    can recovery help healing process of a fractured wrist? i broke wrist 10 days ago. i have typical inflammatory response.

    • Purica says:

      Hello Laura,

      Recovery is designed specifically to improve the entire healing response, and it has been administered, with enhanced healing as a primary consideration, for almost twenty years successfully. We feel very confident that you and your doctor will see significant benefits.

  • Sue says:

    I notice that after a couple of weeks of using the 5 X2/day, I am experiencing more energy and more mentally ‘on the ball’. What ingredient is responsible for that?

    • Purica says:

      Hello Sue,

      We believe that the changes of energy that typically occur when using Recovery are due to positive effects within the digestive tract, primarily because of Nutricol.

  • Kristin says:

    I have osteoarthritis in my left hip that is quite painful. I have been taking curamin in addition to glucosamine/chondroitin – would Recovery be redundant with those supplements, or would it help?

    • Purica says:

      Hello Kirstin,

      Recovery goes above and beyond what you have mentioned, in terms of mechanism of action – see technical monograph:

      As far as redundancy, you would not need to keep taking glucosamine and chondroitin if you took Recovery, if you wish to keep it simple.

  • Elizabeth Skinner says:

    I have controlled high blood pressure. Will Recovery affect this?

    • Purica says:

      Thank you for your email. Recovery is designed to act like somewhat of an adaptogen to help improve functioning of the body. Although we have not conducted formal trials for blood pressure, we have received positive feedback regarding long term use of Recovery from people who also have had high blood pressure.

  • Jennifer says:

    Is it safe for someone with celiac? And a corn intolerance?

    • Purica says:

      Yes, Purica Recovery is gluten free. In regards to the corn intolerance, the Vegan Glucosamine is purified component of Non-GMO Corn, which is safe and produces no allergic responses.

  • Stacy says:

    I use a blood thinner and was wondering if this would change my IRN numbers?
    Thanks

    • Purica says:

      Thanks for your question. Recovery is safe, even with Coumadin/warfarin and will have no effect to IRN. Here is a link to our monograph which you can show to your health care practitioner.

  • Patty says:

    I have an allergy to sulfur. Is Recovery ok to take as it does contain some?
    I have ben using Tylenol arthritis but find its not really working and hard on the kidneys.
    I really want to try Recovery, my Dr. says approves..
    thank you..

    • Purica says:

      Research supports that there have been no known contraindications connected to the use of Recovery. The MSM component of Recovery is naturally occurring sulfur found in plants. Science-based reports of allergies to MSM are not found. Hope this helps.

  • Rona says:

    An MRI just showed grade three degeneration of the meniscus area, and I was told a knee replacement will be necessary. I picked up Recovery, but the powder form. Have only been taking it for three days, but have intense gas.
    Two questions. 1. Will this help the knee and 2. Could it be causing the gas?

    • Purica says:

      Recovery will definitely be of benefit to you but of course when surgeons are recommending knee replacement surgery it of course means that the area had become severely degraded which makes it impossible to say if Recovery will be able to change that prognosis. That being said Recovery® is the number one solution for pain and inflammation and contains Nutricol®, a unique proprietary blend of green tea and grapes. Nutricol® repairs the matrix and membrane of the cell improving nutrient receptivity and healing.

      Minimal side effects may occur with Recovery®. Some may experience a looser stool, flatulence and abdominal gurgling, or other detoxifying symptoms. Simply adjust your dosage levels to ensure your comfort. Begin taking Recovery® with food until your body adjusts. Recovery® is safe, effective and produces outstanding results for those who are consistent in taking it.

  • Cheryl says:

    HI, I am interested in knowing if all of the ingredients are sourced from food and if anything is synthetic such as the vitamin C. Also, can you please let me know if Recovery or your other products are organic? thank you!

    • Purica says:

      Thanks for the question. All of recovery is sourced naturally and none of the forms are synthetic. Ingredients like MSM and Glucosamine are palnt based but are not available in a Certified Organic form. Whenever possible we use organic ingredients. This includes the berries we use in Recovery and our entire Medicinal Mushroom line. http://purica.com/product#power-mushrooms

  • Keri says:

    I have an allergy to suffer and glucosamine and antimflamitories of any kind, even using any lotions with any inflammatory in it. I have IC and because of a car accident I have broken a lot of bones ,arthritis, and I was in a coma for 3 weeks. So my question is do you think I should try Recovery?

    • Purica says:

      Unfortunately if you have an allergy to Glucosamine of any kind we would not advise that you take Recovery as it does contain Glucosamine HCL (processed from corn). Recovery also contains MSM which is an organic form of sulfur found in green foods very different than sulfa drugs.

      All the best,

      Trevor

  • Amy says:

    I am 30 and have had psoriasis for 10+ years, would Recovery help my skin?

    • Purica says:

      Thank you for your question. Although Recovery is not studied for skin conditions we have had very positive feedback. One of the company founders has had a personal experience and I know he would not mind sharing with you. If you care to email him his name is Trevor and can be contacted at service@purica.com

  • Lisa says:

    Alot of arthritis products have Collagen in them- as high as 2750 mg/ day. I noticed recovery doesn’t. What do you use as a replacement for rebuild of collagen? I have arthritis & cysts in my wrists…does this product get rid of cysts too?

    Thanks.

    • Purica says:

      Hello Lisa, Collagen is rebuilt with protein in diet, sulfur (such as MSM) and with necessary input from magnesium and vitamin C dependent mechanisms, among other nutrient dependent factors. Recovery is designed to address all of this. It is possible for some cysts to simply dissolve over time if the underlying issue is addressed effectively.

  • Gigi says:

    I had hip replacement surgery 28 days ago. I have been taking pain killers based on morphine and also Tylenol 2. Now I have been reducing those medications, afraid of addiction. Could Recovery help with pain while I am still recovering from the surgery ? Thank you

    • Purica says:

      Hi there, yes Recovery will help reduce the pain, along with speeding up the healing process. It does this by naturally reducing inflammation and allowing proper blood flow.

  • Dianne Peddle says:

    I have been taking celebrex for osteoarthritis and osteoporosis for years . Will Recovery help me to get off celebrex?

    • Purica says:

      Thank you for your comment Dianne. We are unable to speak on medications however we can say that after 17 years, Recovery is still our number 1 selling product and most people see very positive benefits for pain and inflammation associated with Arthritis.

  • Michele says:

    What form is the Vitamin C? I am allergic to as ascorbic acid and have trouble finding great products that don’t use this laboratory created form of Vitamin C.

    • Purica says:

      Hello, thank you for your question. You actually could not be allergic to ascorbic acid, only antigens remaining from its source material or solvents… ascorbic acid IS vitamin C and humans require it. We use magnesium ascorbate which is buffered (non acidic form of vitamin C)

      Thank you

  • Maggie says:

    Is Recovery safe to take when a person has cancer?

    • Purica says:

      Hello, Although we are not able to discuss Cancer we can tell you it is safe to use. Some doctors will ask you to discontinue use before treatment for their condition.
      Thank you

  • Gillian Andrew says:

    i use Recovery powder for humans.I bought the dog version for a 13 year old arthritic rescue dog, but can’t get him to take even 1/4 tsp in a 2 cup dinner with lots of gravy. What makes it so much more bitter than the human med? There must also be an odour I can’t detect since he won’t even taste the meal. Would the human kind work for the dog? He’s 68lbs; what dose is right?

    • Purica says:

      The SA version of Recovery does not contain any flavours what so ever so is a bit bitter. It is not usual that a dog will not take it if it is mixed in a gravy but some dogs can be picky for sure. The formula is similar but different amounts in the human version but you would use the same amount so about 3/4 tsp of the human version.

  • Robert says:

    Is it safe for diabetics, and will it help the diabetic condition? If so, how?

  • Lori says:

    Hello, I bought the Recovery SA extra strength powder for my 12 year old Shetland Sheepdog. He responds VERY well, but every single time he takes it, he gets diarrhea very bad. I have tried to reduce the powder to just 1/8th tsp, but no luck. He just cannot tolerate magnesium, so I bought another brand of MSM/glucosamine without magnesium and he’s just fine, but the recovery works better for him. Is there such a thing as a form of Recovery without the magnesium, or with a much reduced amount of magnesium? Thanks very much, Lori

    • Purica says:

      Hello Lori, thank you for your message. Unfortunately we do not have a reduced magnesium Recovery SA product. Generally by feeding a lower dose animals respond well to a gradual increase. The one suggestion I would make is stop using for 2 weeks and then start at a very low dose gradually increasing daily. At 1/8th of a teaspoon the Magnesium is so low it should not effect your dog depending on its weight of course.

  • Pablo says:

    Are there any flavor enhancement made to the pills? as in chicken meal or any other meat byproducts in order to enhance the flavor? I ask as my dog has allergies and I am worried that this may flare his condition.

    • Purica says:

      Hello Pablo, Thank you for your question. In the RECOVERY SA Chewables there is a Beef Liver Flavouring, but the powder has no flavouring and is a Vegan formula.
      We always recommend the powder to dogs with allergies.

  • Amy says:

    I was advised not to take this product within two hours of dairy. What is the reason for this?

    • Purica says:

      Hello Amy, the reason for this is dairy blocks absorption, if you take the Recovery an hour before or after consuming Dairy that is completely fine. If you have any more questions you can call our Toll Free: 877-746-9397 or email kate@purica.com

  • Sandra says:

    I’ve been feeling dizzy after taking Recovery for 3 weeks (12 per day as recommended to start). Would it counteract my medication for high blood pressues (Amlodipine)?

    • Purica says:

      Hello Sandra, The Recovery should not effect your BP however we would suggest reducing the dose if you are feeling dizzy. Do you monitor your BP yourself? Feel free to email or call with any questions kate@purica.com 877-746-9397

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