Choline

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General Description:

  • one of the body’s raw ingredients
  • every cell in the body contains components derived from choline

Actions:

  • essential for proper fat metabolism
  • a part of lecithin, which helps to digest, absorb, and carry fats and fat soluble vitamins in the blood
  • necessary for synthesis of nucleic acids
  • minimizes excessive deposits of fat and cholesterol in the liver and arteries
  • essential for the health of the myelin sheaths of the nerves
  • regulates and improves the function of the liver and gallbladder
  • necessary for the production of phospholipid, a substance in the blood
  • useful in the treatment of neuritis
  • can prevent the formation of gallstones
  • useful in the treatment of high blood pressure
  • has been used to treat atherosclerosis, kidney damage, glaucoma, and myasthenia gravis
  • a part of acetylcholine, an important neurotransmitter in the brain and nervous system that regulates a variety of body functions.
  • helps carry fats through the bloodstream and prevent their deposition on the blood vessel walls
  • sometimes termed a lipotropic factor
  • methyl donor in energy metabolism
  • a condition known as tardive dyskinesia may benefit from choline supplementation

Deficiency:

  • no deficiency syndrome exists
  • however, prolonged deficiency may cause high blood pressure, cirrhosis and fatty degeneration of the liver, atherosclerosis, and hardening of the arteries
  • average intake in America is 400-900 mg.

Interactions and Toxicity:

  • relatively non-toxic
  • high doses of choline may aggravate depression
  • mega-doses (15-25 g) may cause gas and diarrhea
  • a quartet of chemicals in the brain influence depression and one of these if acetylcholine for which choline is used to make
  • high doses of choline may stimulate Ach formation which could lead to an imbalance of chemicals in the brain which could then lead to depression or anxiety for that matter
  • choline and morphine and/or anti-depressant drugs are not advisable partnerships

Sources:

  • choline naturally occurs in lecithin
  • widely available, from foods like eggs, to soybeans, to many vegetables and legumes

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